Cellulose is a linear homopolymer consisting of repeating β-d-glucopyranosyl units linked via (1,4) glycosidic bonds. In its pure form, the straight chains are bound closely together by multiple intermolecular hydrogen bonds and van der Waals forces, producing a water-insoluble fibrous or crystalline substance which is relatively inert. The EFSA ANS Panel assessed recently the absorption, distribution, metabolism and excretion (ADME) of celluloses (EFSA, 2018) and draw the following conclusions concerning non-herbivore mammals: cellulose is not absorbed intact in the gastrointestinal tract of animals and humans but is fermented during its passage through the large intestine by the microbiota, with the limited production (9% of the administered dose in the rat) of short-chain fatty acids (mainly acetic acid and succinic acid), hydrogen, carbon dioxide and methane.
Manufacturing HPMC involves a meticulous blend of science and engineering. The process typically starts with high-quality cellulose sourced from cotton linters or wood pulp. This raw material undergoes a series of treatments, including bleaching and alkali treatment, to create a base cellulose. The next step is the critical hydroxypropylation and methylation process, where the cellulose is reacted with propylene oxide and methyl chloride, respectively, under controlled conditions. These reactions introduce hydroxypropyl and methyl groups onto the cellulose backbone, altering its properties significantly. Environmental Sustainability In addition to quality, the HPMC Factory also focuses on sustainability. The factory takes measures to reduce waste and energy consumption, while also implementing eco-friendly practices in its production processes. This commitment to sustainability has not only helped reduce the environmental impact of the factory but has also attracted environmentally conscious customers. The solubility of HEC in cold water is typically slow, often requiring agitation or heating to facilitate dissolutionThe molecular weight of HEC also plays a significant role in its solubility. Lower molecular weight HEC grades tend to dissolve more quickly and completely in water compared to their higher molecular weight counterparts Lower molecular weight HEC grades tend to dissolve more quickly and completely in water compared to their higher molecular weight counterparts
The packaging itself is designed to maintain the integrity of the product during transportation and storage. It typically involves airtight containers that protect the powder from moisture and other environmental factors that could compromise its redispersibility.